MERKURY ARENA LABS
(Tranexamic Acid 500mg)
Tranexamic Acid
Tranexamic Acid reduces and prevents hemorrhage following a tooth extraction in patients with hemophilia. Can also treat women with heavy monthly periods.
Tranexamic Acid Overview
Tranexamic acid is a prescription medicine used to prevent the breakdown of blood clots. Tranexamic acid belongs to a group of drugs called antifibrinolytics which work by preventing the breakdown of blood clots. Tranexamic acid tablets are used to treat women with heavy monthly periods (menstruation) that get in the way of social, leisure, and physical activities.
Tranexamic injectable form to be given directly into a vein (IV) by a healthcare professional and is given immediately before tooth extraction and following tooth extraction. Tranexamic acid injection is used to reduce or prevent hemorrhage and reduce the need for replacement therapy during and following tooth extraction in patients with hemophilia as short-term use (two to eight days).
Common side effects of tranexamic acid include headache, back pain, fatigue, nausea, vomiting, and diarrhea.
Uses of Tranexamic Acid
Tranexamic acid is a prescription medicine used to treat adult women with heavy monthly periods (menstruation) when bleeding gets in the way of social, leisure and physical activities. Tranexamic acid injection is also used to reduce or prevent hemorrhage and reduce the need for replacement therapy during and following tooth extraction in patients with hemophilia as short-term use (two to eight days). This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information
What is tranexamic acid-injection, and how does it work (mechanism of action)?

• Tranexamic acid promotes the clotting of blood and thereby reduces bleeding due to tooth extractions in people with hemophilia. People with hemophilia bleed easily because they lack a specific blood protein necessary for forming blood clots.
• Tranexamic acid is a man-made amino acid derivative that increases blood clotting by preventing the breakdown of fibrin. Fibrin is a protein and an important component of blood clots. It is broken down by another protein called plasmin. Tranexamic acid blocks the action of plasmin on fibrin and thereby prevents the breakdown of fibrin. This leads to stabilization and preservation of fibrin in blood clots. This helps reduce bleeding after a tooth extraction.

What are the side effects of tranexamic acid-injection?
Common side effects of tranexamic acid injection include:

• Nausea.
• Vomiting.
• Diarrhea

Other less common side effects side effects include:

• Allergic dermatitis.
• Giddiness.
• Low blood pressure (hypotension).
• Possible serious side effects include:
• Deep vein thrombosis (blood clot in the leg).
• Pulmonary embolism (blood clot in the lung).
• Cerebral thrombosis.
• Acute renal cortical necrosis.
• Central retinal artery and vein obstruction
• Convulsions.
• Visual impairment.

What is the dosage for tranexamic acid-injection?

• Prior to tooth extraction, tranexamic acid should be administered at a dose of 10 mg per kg body weight of intravenously.
• Thereafter, a dose of 10 mg per kg body weight should be given three to four times daily for 2 to 8 days after tooth extraction.

Which drugs or supplements interact with tranexamic acid-injection?

• Concomitant use with tissue plasminogen activators (used to prevent or treat blood clots) can reduce the effectiveness of tranexamic acid.
• Concomitant use with factor IX complex concentrates or anti-inhibitor coagulant concentrates that promote blood clots is not recommended due to the increased risk of blood clots.